This Blog is created for the updation of knowledge on Quality Assurance, current Good Manufacturing Practices (cGMP) and current Updates from all regulatory authorities. Also one can archive Standard Operating Procedures (SOPs), specification and pharma jobs etc. for any Pharma plant.
Tuesday, December 7, 2010
Cleaning of Filter of all AHU
1.0Purpose: To provide cleaning instruction of various types of filters in AHU as per safety and cGMP requirements.
2.0Objective : To provide documented procedure for cleaning instruction of various types of filters in AHU as per safety and cGMP requirements
3.0 Scope : This SOP covers the instructions for cleaning of pre-filters and fine filters of all AHU. The SOP specifies the responsibilities of staff for the various functions outlined here under.
·Primary: Technician Engineering
·Secondary: Manager Engineering
Ensure prior to clean:
ØEnsure that area connected to respective AHU is not in any use by its respective user department.
ØIntimate user department.
ØStop the respective AHU and remove its fuses and put a board “EQUIPMENT IS UNDER MAINTENANCE” on the MCC feeder as well as on the AHU.
ØBy pressing the local push button, ensure the respective AHU can not be started.
·Cleaning Procedure for pre-filter and fine filter:
ØRemove the filters to be cleaned from the AHU by unscrewing all its bolts.
ØNumber the filters with marker pen as per its original location so that they can be refixed on their same location.
ØTake all the filters to the filter cleaning room.
ØWear rubber gloves and eye goggles.
ØSpray compressed air on the filter in the direction opposite to the air flow direction when the AHU is under working condition. Continue this process as per requirement of cleaning. Maintain air pressure in the range of 2 to 3 kg/cm2 g.
ØThen clean the filters with the help of tap water.
ØThen again spray compressed air on the filter in both the directions.Continue this spray unless all the water is removed from the filter and filter is thoroughly clean.
ØKeep the cleaned filter on the rack for drying for 1 to 1.5 hrs.
ØAlso clean all the section of AHU like return air section, supply air section, fan – motor section, cooling coil section and all the sides of AHU by cotton dipped in potable water and final drying using dry cotton waste.
ØRefix all the filters as per its number on their original position.
ØAlso clean the filter cleaning room.
ØInsert the fuses of the AHU and ensure that there is no leakage by physical checking from any sides of the filters.
·SAFETY, HEALTH AND ENVIRONMENTAL ASPECTS:
ØBefore cleaning the filter:
RWear rubber gloves and eye goggles.
RRemove the fuses of the respective AHU.
RPut a board on the MCC feeder and AHU that “AHU IS UNDER MAINTENANCE.”